Day: January 10, 2018

Tallahassee city commission wraps up annual retreat – WTXL ABC 27

Crime is down too. Tallahassee Police chief Michael DeLeo says it decreased nearly 14 percent in 2017 compared to the year before. One of the city’s goals this year is to find a location for a new police headquarters.

The Capital City is ranked 19th in the nation when it comes to economic growth per capita.

“It’s not been dependent upon what the state has done or anybody else,” said Tallahassee mayor Andrew Gillum. “It’s been dependent upon what we’ve done here as a community, and I think that’s the best kind of growth you can ask for.”

Elsewhere, development continues to be a hot topic in Tallahassee. The city says there are 95 projects in different phases throughout the city.

Video Gallery – WTXL Video Template

“Come play basketball and have a park and a playground that’s part of the overall campus and footprint with what the police facility would be, so that way, we’re just part of the normal environment,” said DeLeo. “We’re really trying to create more and more opportunity when the only time someone comes into contact with the police department or a police officer is when something’s wrong, but just as part of their normal daily lives, and that’s how you develop relationships.”

LSU’s Derrius Guice entering NFL draft –

LSU's Derrius Guice entering NFL draft

Guice announced his decision late Wednesday afternoon in a video posted on Twitter. The junior rushed for 3,074 yards and 29 touchdowns on 471 career carries, starting most of the past two seasons for his hometown Tigers. 's Mel Kiper rates Guice
Derrius Guice declares for 2018
LSU RB Derrius Guice, Likely Early-Round Pick, Declares for NFL DraftSports Illustrated
LSU's Derrius Guice declares for 2018 NFL
The Advocate -Washington Post -Sporting News -247Sports
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BBC bags most-watched show of 2017 despite losing Bake Off – Winsford Guardian

But it was enough for the BBC to hold on to its title as the home of the biggest TV audience of the year.

The last ever episode of the David Tennant-fronted crime thriller was watched by 11.6 million – the biggest audience for any TV drama in 2017.

All figures have been compiled from ratings published by Barb, and include +1 and HD data where appropriate.

An analysis of the top 40 biggest audiences of 2017 by the Press Association shows that 27 were for programmes broadcast on BBC One, including all seven episodes of Blue Planet II.

Close behind in third place was ITV’s I’m a Celebrity… Get Me Out of Here!, which attracted an audience of 12.7 million for its launch episode.

Channel 4 did not make the top 40, despite buying the rights to The Great British Bake Off.

A chart-topping 14 million people saw episode one of the wildlife series Blue Planet II, which included dramatic footage of walruses fighting to find a home, along with dazzling scenes of surfing dolphins and a sex-changing fish.

The BBC shrugged off the loss of The Great British Bake Off in 2017 to once again broadcast the most-watched TV programme of the year – with a little help from a walrus mother and her pup.

Overall in 2017 the BBC broadcast the year’s most-watched documentary (Blue Planet II), light entertainment (Strictly Come Dancing) and live event (the One Love Manchester charity concert).

Texas A&M research shows biological clocks could improve brain cancer treatment – EurekAlert (press release)

“We work on a model system, and the reason to do that is that we can make progress quickly, and we always hope that what we’re working on will lead to something useful, and I think this is a prime example of how putting effort into basic research can pay off,” Bell-Pedersen said. “We’re very hopeful and encouraged by our data that we’ll find a treatment.”

This reduced toxicity is important, because a drug to inhibit the cancer-promoting activity of this protein was tested but found to be too harmful, with too many side effects. “If treatment with the drug can be timed to when the normal glial cells naturally have low activity of p38 MAPK, the addition of the drug might not be as toxic for these cells, and yet would still be very effective on the cancerous cells,” Earnest said.

These findings indicate that glioblastoma might be a good candidate for chronochemotherapy, meaning treating cancer at specific times of day to get the most impact.

Texas A&M biologist Deborah Bell-Pedersen, PhD, a co-corresponding author on the study, found in her previous research that the biological clock in the model fungal system Neurospora crassa controls daily rhythms in the activity of a signaling molecule, called p38 mitogen activated protein kinase (MAPK). This signaling protein plays a role in glioblastoma’s highly invasive and aggressive properties.

Biological clocks throughout the body play a major role in human health and performance, from sleep and energy use to how food is metabolized and even stroke severity. Now, Texas A&M University researchers found that circadian rhythms could hold the key to novel therapies for glioblastoma, the most prevalent type of brain cancer in adults–and one with a grim prognosis.

IMAGE: Scan of a glioblastoma tumor. view more 

In the new research, David J. Earnest, PhD, a mammalian biological clocks expert at the Texas A&M College of Medicine and co-corresponding author on the study, collaborated with Bell-Pedersen to show that the clock controls daily rhythms in p38 MAPK activity in a variety of mammalian cells as well, including normal glial cells, the supporting “helper” cells surrounding neurons.

Francis Coquelin: Valencia to sign Arsenal midfielder, says Wenger – BBC Sport

BBC Sport

Francis Coquelin: Valencia to sign Arsenal midfielder, says Wenger
BBC Sport
Valencia are set to sign French midfielder Francis Coquelin from Arsenal, Arsene Wenger has confirmed. The 26-year-old leaves for Spain in what is expected to be a £12m deal, having joined the Gunners as a youth player in 2008. He made 105 Premier
Arsene Wenger confirms Arsenal transfer after Chelsea drawDaily Star
Arsene Wenger hints at no new Arsenal signing to replace Francis CoquelinEvening Standard
Arsene Wenger reveals plan to replace Arsenal midfielder Francis Coquelin after confirming Valencia
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Netflix is goofing off with lab-grown bodies at CES – The Verge

It turns out, Netflix’s idea was to construct an elaborate faux-serious campaign, including a partnership with the drama’s fictional company Psychasec, and the collaborative booth they’re presenting at CES is a pretend exhibition area for Psychasec’s “sleeve” products. A sleeve, in the Altered Carbon universe, is a spare body you can transfer your consciousness into — because, as the tagline smugly proclaims, “no body lives forever.”

I had to get some background on what Altered Carbon, based on a cyberpunk sci-fi novel of the same name, was about from my colleague Andrew Liptak. Here’s his summary:

Walking through the Altered Carbon booth, however, was bemusing, and not in an especially good way. The young guides populating the fake store are dressed in all white, and they’re trying their utmost to maintain a serious air to their pretense. It’s a very goofy experience to be among people who are fully conscious of the ridiculousness of their actions. Nobody at CES was really buying the idea that they were being sold new sleeves for their souls, though there were plenty of intrigued onlookers. Guess that’s what happens when you show a little bit of flesh, whether it’s a real or simulated human.

Among the deluge of CES news releases this week, one stood out to me because it made little sense: Netflix was bringing its upcoming Altered Carbon series to the big Las Vegas exhibition. How do you bring a drama series to a hardware show?

Set 300 years in the future, it follows a dead soldier named Takeshi Kovacs (Suicide Squad’s Joel Kinnaman). In this future, people can digitally transfer their consciousness from one body to the next by way of an implant called a Stack. Kovacs, killed on a distant planet and awoken on Earth, discovers that he’s been hired to help Earth’s wealthiest man, Laurens Bancroft (James Purefoy), investigate his own death, which the police believe is a suicide. The show’s central McGuffin is at the heart of the mystery — both in the novel and in the series — and the world. Religious groups have condemned the company behind the body transfers, saying that the technology is immoral, and that lab-grown bodies and clones are an affront.

I’m told these brand activations are approaching ubiquity at sci-fi conventions like those in San Diego and New York, but for the tech-focused Consumer Electronics Show, it feels like an alien experience. We’re a much more cynical crowd.

2 Westside Jacksonville gunshot victims are critical – Florida Times-Union

2 Westside Jacksonville gunshot victims are critical
Florida Times-Union
Two men suffered life-threatening gunshot wounds Tuesday night at a Westside trailer park, according to the Jacksonville Sheriff's Office. Few details have been released, but police were initially called to a shooting about 8:45 p.m. at the Oak Ridge

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Golden Globes Shows Gender Parity Fight Starts With the Greenlight – Variety

Daniel Holloway and Debra Birnbaum contributed to this report.

FX’s limited series “Feud: Bette and Joan,” the story of two aging Hollywood legends starring Jessica Lange and Susan Sarandon, broke every rule in the book (actresses over 50, oh my), and yet it was successful for FX and has gone toe to toe with “Big Little Lies” in the awards derby.

“What happens is, pressure gives way to change, and if you always have somebody saying: ‘Hello? Please do better,’ a lot of people can be moved to act. It’s powerful,” Murphy said. The parade of talent onstage at the Globes on Sunday night “was very important. It meant something to me,” Murphy told Variety.

Murphy pointed to his own career experience as evidence that change has long been under way as women slowly but surely rise into the C-suites. He cites Fox Television Group chairman Dana Walden as his single most important influence.

“We have been known for a long time for having shows on the air that have strong, powerful women at the forefront,” said ABC Entertainment president Channing Dungey. “But what I want to also think about is how do we continue to show workplaces that are diverse, where men and women are working together, where we are leading by example. If we’re saying 50-50 by 2020, then we should really be showing that on the air as well.”

The #MeToo and time’s up movements have galvanized powerful women in the entertainment industry to work harder to effect social change and combat sexual
misconduct in the workplace. But on the heels of a historic night at the Golden Globe Awards, insiders are still questioning whether that progressive spirit will extend all the way up to the most supreme power in Hollywood: the greenlight.

“I’m especially proud and inspired by all the women who have felt strong enough and empowered enough to speak up and share their personal stories,” Winfrey said in a stunning speech after receiving the Cecil B. DeMille Award that had many in the crowd hoping she’d make a run for political office.

“Putting women at the center of our stories isn’t just the right thing to do — it’s good business.”
Nicole Kidman

Betsy Beers, partner with über-producer Rhimes in the Shondaland banner, was among those who cheered as women took the Globes stage at the Beverly Hilton.

What too much business travel can do to your health – New York Post

“To make it easier for yourself, you may want to consider having a meaningful conversation with significant others in your world, what can you do to create efficiencies at home so it won’t feel disruptive? Maybe occasionally you can travel with your family. Especially if you can take the trip on a weekend so that way it becomes more joyful,” says Cohen.

In addition to declining mental health, the researchers found those who drink alcohol while away on business could be more likely to develop addictive tendencies and dependency than those who don’t travel as much. The study — which examined the health records of 18,328 employees who took a health assessment through their workplace corporate wellness program — also found mental health and behavior are negatively affected the more days a person is away from home.

People who take work trips two weeks or more a month report more symptoms of anxiety and depression and are more likely to smoke and have difficulty sleeping, compared to those who travel one to six nights a month, according to a new study by Columbia University’s Mailman School of Public Health and City University of New York.

“The goal is to demonstrate to your boss that traveling less and working from home or at the office has the potential to enhance productivity and cost savings,” career coach Roy Cohen tells Moneyish. “When you’re traveling you’re out of pocket especially during the winter so the best time to make this request is during a period of horrible weather because that’s incredibly disruptive to companies.”

“Although business travel can be seen as a job benefit and can lead to occupational advancement, there is a growing literature showing that extensive business travel is associated with risk of chronic diseases associated with lifestyle factors,” said Andrew Rundle, an associate professor of epidemiology at the Mailman School of Public Health.

When it comes to your personal life, find a way to incorporate family into time away and make a plan, Cohen suggests.

Trump urged not to scrap Iran nuclear deal, but will he listen? – CNN


Trump urged not to scrap Iran nuclear deal, but will he listen?
Washington (CNN) President Donald Trump's top national security advisers are encouraging him to comply with the terms of the 2015 Iran nuclear deal and renew temporary waivers for US sanctions against Iran ahead of Friday's key legal deadline, US
AP sources: Trump to extend sanctions relief for IranWashington Post
As new deadline looms, Trump is expected to stay in Iran nuclear deal despite reservationsLos Angeles Times
Top Dem: No agreement on Iran bill as nuclear deal deadline approachesThe Hill
Daily Beast -The Atlantic -Reuters -HuffPost
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