Multidrug-resistant Malaria expanding in Southeast Asia – study


PHOTO FILE: Saopheles minimus mosquitoes at a laboratory in the Ministry of Public Health in Bangkok, Thailand, November 9, 2017. REUTERS / Athit Perawongmetha

LONDON (Reuters) – Malaria traits that are against two main anti-muscular medicines are becoming more prevalent in Vietnam, Laos and northern Thailand after they have quickly gone from Cambodia, scientists warned Monday.

Using genomic surveillance to track the spread of drug-resistant malaria, scientists found that the pressure, known as KEL1 / PLA1, emerged and that new genetic mutations emerged that could lead to the emergence of drug-resistant malaria. it would still be more resistant to drugs.

“We discovered (that he was) fiercely, instead of local malaria parasites, and that the biggest pressure was in Vietnam, Laos and northern Thailand,” said Roberto Amato, who worked a team from British Wellcome Institute Sanger and University of Oxford and Mahidol of Thailand University.

Plasmodium parasites cause mosquitoes carried by malaria and are spread through their blood glues.

There were almost 220 million malaria infections in 2017, according to World Health Organization estimates, of which 400,000 were killed. The majority of cases and deaths are in children and children in sub-Saharan Africa.

Malaria can be successfully treated with medication if it is caught early, but resistance against anti-muscular drugs is growing in many parts of the world, especially in Southeast Asia.

The first line treatment for malaria in many parts of Asia over the past decade is a mixture of dihydroartemisinin and pipes, also known as DHA-PPQ. Researchers in a previous work have found that pressure and malaria have emerged throughout Cambodia between 2007 and 2013. This latest research, published in Lancet Infectious Disease, found that it has set limits. cross and paste up.

“The speed of these malaria resistant parasites in Southeast Asia is a matter of great concern,” said Olivo Miotto, who led the work.

“Other drugs can be effective at the moment but the situation is very fragile and this study shows that urgent action is needed,” he said.

Reporting by Kate Kelland, edited by Susan Fenton

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(tagsToTranslate) US (t) HEALTH (t) MALARIA (t) ANSWER (t) Switzerland (t) Health / Medicine (t) Western Europe (t) Infectious Diseases (t) Asia / Pacific (t) Thailand (t) Laos (t) Europe (t) Pharmaceuticals and Medical Research (TRBC) (t) Science (t) Vietnam (t) Drug Development and Device (t) United Kingdom (t) Malaria (t) Cambodia


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